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Psychological

and Physiological

Trauma Research

 

 

Seize Your Journeys

 

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Traumatic stress is found in many competent, healthy, strong, good people.  No one can completely protect themselves from traumatic experiences.  Many people have long-lasting problems following exposure to trauma.  Up to 8% of persons will have PTSD at some time in their lives. People who react to traumas are not going crazy.  What is happening to them is part of a set of common symptoms and problems that are connected with being in a traumatic situation, and thus, is a normal reaction to abnormal events and experiences.  Having symptoms after a traumatic event is NOT a sign of personal weakness.  Given exposure to a trauma that is bad enough, probably all people would develop PTSD.

By understanding trauma symptoms better, a person can become less fearful of them and better able to manage them. By recognizing the effects of trauma and knowing more about symptoms, a person will be better able to decide about getting treatment.

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Circadian Rhythm Sleep Disorder

(formerly Sleep-Wake Schedule Disorder)

 Diagnostic Features

            “The essential feature of Circadian Rhythm Sleep Disorder is a persistent or recurrent pattern of sleep disruption that results from a mismatch between the individual’s endogenous circadian sleep-wake system on the one hand, and exogenous demands regarding the timing and duration of sleep on the other (Criterion A).  In contrast to other primary Sleep Disorders, circadian Rhythm Sleep Disorder does not result from the mechanisms generating sleep and wakefulness per se.  As a result of this circadian mismatch, individuals with this disorder may complain of insomnia at certain times during the day and excessive sleepiness at other times, with resulting impairment in social, occupational, or other important areas of functioning or marked subjective distress (Criterion B).  The sleep problems are not better accounted for by other Sleep Disorders or other mental disorders (Criterion C) and are not due to the direct physiological effects of a substance or a general condition (Criterion D).

The diagnosis of Circadian Rhythm Sleep Disorder should be reserved for those presentations in which the individual has significant social or occupational impairment or marked distress related to the sleep disturbance.  Individuals vary widely in their ability to adapt to circadian changes and requirements.  Many, if not most, individuals with circadian-related symptoms of sleep disturbance do not seek treatment and do not have symptoms of sufficient severity to warrant a diagnosis.  Those who prevent for evaluation because of this disorder are most often troubled by the severity or persistence of their symptoms.  For example, it is not unusual for shift workers to present for evaluation after falling asleep while on the job or while driving.

The diagnosis of Circadian Rhythm Sleep disorder rests primarily on the clinical history, including the pattern of work, sleep, naps, and ‘free time.”  The history should also examine past attempts at coping with symptoms, such as attempts at advancing the sleep-wake schedule in delayed Sleep Phase Type.  Prospective sleep-wake diaries or sleep charts are often a useful adjunct to diagnosis.

 Subtypes

Delayed Sleep Phase Type.  This type of Circadian Rhythm Sleep disorder results from an endogenous sleep-wake cycle that is delayed relative to the demands of society.  Measurement of endogenous circadian rhythms (e.g., core body temperature) reflects this delay.  Individuals with this subtype (“night owls”) are hypothesized to have an abnormally diminished ability to phase-advance sleep-wake hours (i.e., to move sleep and wakefulness to earlier clock times).  As a result, these individuals are ‘locked in” to habitually late sleep hours and cannot move these sleep hours forward to an earlier time.  The circadian phase of sleep is stable:  individuals will fall asleep and awaken at consistent, albeit delayed, times when left to their own schedule (e.g., on weekends or vacations).  Affected individuals complain of difficulty falling asleep at socially acceptable hours, but once sleep is initiated, it is normal.  There is no concomitant difficulty awakening at socially acceptable hours (e.g., multiple alarm clocks are often unable to arouse the individual).  Because many individual with this disorder will be chronically sleep deprived, sleepiness during the desired wake period may occur.

Jet Lag Type.  In this type of Circadian Rhythm sleep Disorder, the endogenous circadian sleep-wake cycle is normal and the disturbance arises from conflict between the pattern of sleep and wakefulness generated by the circadian system and the pattern of sleep and wakefulness required by a new time zone.  Individuals with this type complain of a mismatch between desired and required hours of sleep and wakefulness.  The severity of the mismatch is proportional to the number of time zones traveled through, with maximal difficulties often noted after traveling through eight or more time zones in less than 24 hours.  Eastward travel (advancing sleep-wake hours) is typically more difficult for most individuals to tolerate than westward travel (delaying sleep-wake hours).

Shift Work Type.  In this type of Circadian Rhythm Sleep Disorder, the endogenous circadian sleep-wake cycle is normal and the disturbance arises from conflict between the pattern of sleep and wakefulness generated by the circadian system and the desired pattern of sleep and wakefulness required by shift work.  Rotating-shift schedules are the most disruptive because they force sleep and wakefulness into aberrant circadian positions and prevent any consistent adjustment.  Night- and rotating-shift workers typically have a shorter sleep duration and more frequent disturbances in sleep continuity than morning and afternoon workers.  Conversely, there may also be sleepiness during the desired wake period, that is, in the middle of the night work shift.  The circadian mismatch of the Shift Work Type is further exacerbated by insufficient sleep time, social, and family demands, and environmental disturbances (e.g., telephone, traffic noise) during intended sleep times.

Unspecified Type.  This type of Circadian Rhythm Sleep Disorder should be indicated if another pattern of circadian sleep disturbance (e.g., advanced sleep phase, non-24-hour sleep-wake pattern, or irregular sleep-wake pattern) is present.  An “advanced sleep phase pattern” is the analog of Delayed Sleep Phase Type, but in the opposite direction: individuals complain of an inability to stay awake in the evening and spontaneous awakening in the early morning hours.  “Non-24-hour sleep-wake pattern” denotes a free-running cycle:  the sleep-wake schedule follows the endogenous circadian rhythm period of approximately 24-25 hours despite the presence of 24-hour time cues in the environment.  In contrast to the stable sleep-wake pattern of the Delayed or advanced sleep phase types, these individuals’ sleep-wake schedules become progressively delayed relative to the 24-hour clock, resulting in a changing sleep-wake pattern over successive days.  “Irregular sleep-wake pattern” indicated the absence of an identifiable pattern of sleep and wakefulness.

 Associated Features and Disorders

Associated descriptive features and mental disorders.  In Delayed Sleep Phase Type, individuals frequently go to bed later and wake up later on weekends or during vacations, with a reduction in sleep-onset difficulties and difficulty awakening.  They will typically give many examples of school, work, and social difficulties arising from their inability to awaken at socially desired times.  If awakened earlier than the time dictated by the circadian timekeeping system, the individual may demonstrate “sleep drunkenness” (i.e., extreme difficulty awakening, confusion, and inappropriate behavior).  Performance often also follows a delayed phase, with peak efficiency occurring in late-evening hours.

            Jet Lag and Shift Work Types may be more common in individuals who are “morning types.”  Performance is often impaired during desired waking hours, following the pattern that would be predicted by the underlying endogenous circadian rhythms.  Jet lag is often accompanied by nonspecified symptoms (e.g., headache, fatigue, indigestion) that relate to travel conditions, such as sleep deprivation, alcohol and caffeine use, and decreased ambient air pressure in airplane cabins.  Dysfunction in occupational, family, and social roles is often observed in individuals who have difficulty coping with shift work.  Individuals with any Circadian Rhythm Sleep Disorder may have a history of alcohol, sedative-hypnotic, or stimulant use resulting from attempts to control their inappropriately phased sleep-wake tendencies.  The use of these substances may in turn exacerbate the Circadian Rhythm Sleep Disorder.

            Delayed Sleep Phase Type has been associated with schizoid, schizotypical, and avoidant personality features, particularly in adolescents.  “Non-24-hour sleep-wake pattern” and “irregular sleep-wake pattern” have also been associated with these same features.  Jet Lag and Shift Work Type may precipitate or exacerbate a Manic or Major Depressive Episode or an episode of a Psychotic Disorder.

 Diagnostic and Statistical Manual of Mental Disorders DSM-IV. 1994.  4th ed.  Washington, D.C.: American Psychiatric Association.

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Secure Attachments as a Defense Against Trauma

 “All people mature and thrive in a social context that has profound effects on how they cope with life’s stresses.  Particularly early in life, the social context plays a critical role in suffering an individual against stressful situations, and in building the psychological and biological capacities to deal with further stresses.  The primary function of parents can be thought of as helping children modulate their arousal by attuned and well-timed provision of playing, feeding, comforting, touching, looking, cleaning, and resting—in short, by teaching them skills that will gradually help them modulate their own arousal.  Secure attachment bonds serve as primary defenses against trauma-induced psychopathology in both children and adults (Finkelhor & Browne, 1984).  In children who have been exposed to severe stressors, the quality of the parental bond is probably the single most important determinant of long-term damage (McFarlane, 1988).”

van der Kolk, Bessel, Alexander C. McFarlane, and Lars Weisaeth, eds.  1996. Traumatic stress: The effects of overwhelming experience on mind, body, and society.  New York and London: Guilford Press. .p. 185

 Affect Dysregulation in Traumatized Individuals

“As children mature, they gradually become less vulnerable to over-stimulation and learn to tolerate higher levels of excitement.  Over time, their need for physical proximity to their primary caregivers to maintain comfort decreases, and children start spending more time playing with their peers and with their fathers (Field, 1985). Secure children learn how to take care of themselves effectively as long as the environment is more or less predictable; simultaneously, they learn how to get help when they are distressed.  In contrast, avoidant children learn how to organize their behavior effectively under ordinary conditions, but they remain unable to communicate or interpret emotional signals.  In other words, they know how to handle cognition, but not affect (Crittenden, 1994

            Cole and Putnam (1992) have proposed that people’s core concepts of themselves are defined to a substantial degree by their capacity to regulate their internal states and by their behavioral responses to external stress.  The lack of development, or loss, of self-regulatory processes in abused children leads to problems with self-definition: (1) disturbances of the sense of self, such as a sense of separateness, loss of autobiographical memories, and disturbances of body image; (2) poorly modulated affect and impulse control, including aggression against self and others; and (3) insecurity in relationships, such as trouble functioning in social settings; they tend either to draw attention to themselves or to withdraw from social interactions.  Thus, they tend to display either angry, threatening, fearless, acting-out behavior or meek, submissive, fearful, incompetent behavior.  Problems in articulating cause and effect make it hard for them to appreciate their own contributions to their problems and set the stage for paranoid attributions.”

van der Kolk, Bessel, Alexander C. McFarlane, and Lars Weisaeth, eds.  1996. Traumatic stress: The effects o overwhelming experience on mind, body, and society.  New York and London: Guilford Press. .p. 187

 Manifestations of the Absence of Self-Regulation

“The lack or loss of self-regulation is possibly the most far-reaching effect of psychological trauma in both children and adults.  The DSM-IV field trials for PTSD clearly demonstrated that the younger the age at which the trauma occurred, and the longer its duration, the more likely people were to have long-term problems with the regulation of anger, anxiety, and sexual impulses (van der Kolk, Roth, Pelcovitz, & Mandel, 1993).  Pitman, Orr, and Shalev (1993) have pointed out that in PTSD, hyperarousal goes well beyond simple conditioning.  The fact that the stimuli that precipitate emergency responses are not conditioned enough and that many triggers not directly related to the traumatic experience may precipitate extreme reactions is merely the beginning of the problem.  Loss/lack of self-regulation may be expressed in many different ways: as a loss of ability to focus on appropriate stimuli; as attentional problems; as an inability to inhibit action when aroused (loss of impulse control); or as uncontrollable feelings of rage, anger, or sadness.  The results of a study by McFarlane, Weber, and Clark (1993) of event-related potentials in people with PTSD illustrate these various effects.”

Van der Kolk, Bessel, Alexander C. McFarlane, and Lars Weisaeth, eds.  1996. Traumatic stress: The effects o overwhelming experience on mind, body, and society.  New York and London: Guilford Press. .p. 187

  Self-Mutilation

 Eating Disorders

 Substance Abuse

 Dissociation

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Substance Abuse

Features

“The essential feature of Substance Abuse is a maladaptive pattern of substance use manifested by recurrent and significant adverse consequences related to the repeated use of substances.  In order for an Abuse criterion to be met, the substance-related problem must have occurred repeatedly during the same 12-month period or been persistent.  There may be repeated failure to fulfill major role obligations, repeated use in situations in which it is physically hazardous, multiple legal problems, and recurrent social and interpersonal problems (Criterion A).  Unlike the criteria for Substance Dependence, the criteria for Substance Abuse do not include only the harmful consequences of repeated use.  A diagnosis of Substance Abuse is preempted by the diagnosis of Substance Dependence if the individual’s pattern of substance use has ever met the criteria for Dependence for that class of substances (Criterion B).  Although a diagnosis of Substance Abuse is more likely in individuals who have only recently started taking the substance, some individuals continue to have substance-related adverse social consequences over a long period of time without developing evidence of Substance Dependence.  The category of Substance Abuse does not apply to caffeine and nicotine.  The term abuse should be applied only to a pattern of substance use that meets the criteria for this disorder; the term should not be used as a synonym for “use”,” misuse,” or “hazardous use.”

The individual may repeatedly demonstrate intoxication or other substance-related symptoms when expected to fulfill major role obligations at work, school, or home (Criterion A1).  There may be repeated absences or poor work performance related to recurrent hangovers.  A student might have substance-related absences, suspensions, or expulsions from school.  While intoxicated, the individual may neglect children or household duties.  The person may repeatedly be intoxicated in situations that are physically hazardous (.e.g., while driving a car, operating machinery, or engaging in risky recreational behavior such as swimming or rock climbing) (Criterion A2). There may be recurrent substance-related legal problems (e.g., arrests for disorderly conduct, assault and battery, driving under the influence) (Criterion A3).  The person may continue to use the substance despite a history of undesirable persistent or recurrent social or interpersonal consequences (e.g., marital difficulties or divorce, verbal or physical fights) (Criterion A4).

Criteria for Substance Abuse

A. A maladaptive pattern of substance use leading to clinically significant impairment or distress, as manifestd by one (or More) of the following, occurring within a 12-month period:

(1) Recurrent substance use resulting in a failure to fulfill major role obligations at work, school, or home (e.g., repeated absences or poor work performance related to substance use; substance-related absences, suspensions, or expulsions from school; neglect of children or household)

(2) Recurrent substance use in situations in which it is physically hazardous (e.g., driving an automobile or operating a machine when impaired by substance use)

(3) Recurrent substance-related legal problems (e.g., arrests for substance-related disorderly conduct)

(4) Continued substance use despite having persistent or recurrent social or interpersonal problems caused or exacerbated by the effects of the substance (e.g., personal problems caused or exacerbated by the effects of the substance (e.g., arguments with spouse about consequences of intoxication, physical fights)

B. The symptoms have never met the criteria for Substance Dependence for this class of substance.” (p. 198-199)

American Psychiatric Association. 2000. Diagnostic and statistical manual of mental disorders. 4th ed. Washington, D.C.: American Psychiatric Association.

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EMDR-DID-PTSD

     (defined)

 EMDR

Eye Movement Desensitization and Reprocessing

"Eye Movement Desensitization and Reprocessing (EMDR)1 integrates elements of many effective psychotherapies in structured protocols that are designed to maximize treatment effects. These include psychodynamic, cognitive behavioral, interpersonal, experiential, and body-centered therapies2. EMDR is an information processing therapy and uses an eight phase approach.

During EMDR1 the client attends to past and present experiences in brief sequential doses while simultaneously focusing on an external stimulus. Then the client is instructed to let new material become the focus of the next set of dual attention. This sequence of dual attention and personal association is repeated many times in the session.

Eight Phases of Treatment

The first phase is a history taking session during which the therapist assesses the client's readiness for EMDR and develops a treatment plan. Client and therapist identify possible targets for EMDR processing. These include recent distressing events, current situations that elicit emotional disturbance, related historical incidents, and the development of specific skills and behaviors that will be needed by the client in future situations.

During the second phase of treatment, the therapist ensures that the client has adequate methods of handling emotional distress and good coping skills, and that the client is in a relatively stable state. If further stabilization is required, or if additional skills are needed, therapy focuses on providing these. The client is then able to use stress reducing techniques whenever necessary, during or between sessions. However, one goal is not to need these techniques once therapy is complete.

In phase three through six, a target is identified and processed using EMDR procedures. These involve the client identifying the most vivid visual image related to the memory (if available), a negative belief about self, related emotions and body sensations. The client also identifies a preferred positive belief. The validity of the positive belief is rated, as is the intensity of the negative emotions.

After this, the client is instructed to focus on the image, negative thought, and body sensations while simultaneously moving his/her eyes back and forth following the therapist's fingers as they move across his/her field of vision for 20-30 seconds or more, depending upon the need of the client. Although eye movements are the most commonly used external stimulus, therapists often use auditory tones, tapping, or other types of tactile stimulation. The kind of dual attention and the length of each set is customized to the need of the client. The client is instructed to just notice whatever happens. After this, the clinician instructs the client to let his/her mind go blank and to notice whatever thought, feeling, image, memory, or sensation comes to mind. Depending upon the client's report the clinician will facilitate the next focus of attention. In most cases a client-directed association process is encouraged. This is repeated numerous times throughout the session. If the client becomes distressed or has difficulty with the process, the therapist follows established procedures to help the client resume processing. When the client reports no distress related to the targeted memory, the clinician asks him/her to think of the preferred positive belief that was identified at the beginning of the session, or a better one if it has emerged, and to focus on the incident, while simultaneously engaging in the eye movements. After several sets, clients generally report increased confidence in this positive belief. The therapist checks with the client regarding body sensations. If there are negative sensations, these are processed as above. If there are positive sensations, they are further enhanced.

In phase seven, closure, the therapist asks the client to keep a journal during the week to document any related material that may arise and reminds the client of the self-calming activities that were mastered in phase two.

The next session begins with phase eight, re-evaluation of the previous work, and of progress since the previous session. EMDR treatment ensures processing of all related historical events, current incidents that elicit distress, and future scenarios that will require different responses. The overall goal is produce the most comprehensive and profound treatment effects in the shortest period of time, while simultaneously maintaining a stable client within a balanced system.

After EMDR processing, clients generally report that the emotional distress related to the memory has been eliminated, or greatly decreased, and that they have gained important cognitive insights. Importantly, these emotional and cognitive changes usually result in spontaneous behavioral and personal change, which are further enhanced with standard EMDR procedures." www.emdr.com

1Shapiro, F. (2001). Eye Movement Desensitization and Reprocessing: Basic Principles, Protocols and Procedures (2nd ed.). New York: Guilford Press.

2Shapiro, F. (2002). EMDR as an Integrative Psychotherapy Approach: Experts of Diverse Orientations Explore the Paradigm Prism. Washington, DC: American Psychological Association Books.

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Posttraumatic Stress Disorder

"The essential feature of Posttraumatic Stress Disorder us the development of characteristic symptoms following exposure to an extreme traumatic stressor involving direct personal experience of an event that involves actual or threatened death or serious injury, or other threat to one's physical integrity; or witnessing an event that involves death, injury, or a threat to the physical integrity of another person; or learning about unexpected or violent death, serious harm, or threat of death or injury experienced by a family member or other close associate (Criteria A1).  The person's response to the event must involve intense fear, helplessness, or horror (or in children, the response must involve disorganized or agitated behavior) (Criterion A2).  The characteristic symptoms resulting from the exposure to the extreme trauma include persistent reexperiencing of the traumatic event (Criterion E), and the disturbance must cause clinically significant distress or impairment in social, occupational, or other important areas of functioning (Criterion F).

Traumatic events that are experienced directly include, but are not limited to, military combat, violent personal assault (sexual assault, physical attack, robbery, mugging), being kidnapped, being taken hostage, terrorist attack, torture, incarceration as a prisoner of war or in a concentration camp, natural or manmade disasters, severe automobile accidents, or being diagnosed with a life-threatening illness.  For children, sexually traumatic events may include developmentally inappropriate sexual experiences without threatened or actual violence or injury.  Witnessed events include, but are not limited to, observing the serious injury or unnatural death of another person due to violent assault, accident, war, or disaster or unexpectedly witnessing a dead body or body parts.  Events experienced by others that are learned about include, but are not limited to, violent personal assault, serious accident, or serious injury experienced y a family member or a close friend; learning about the sudden, unexpected death of a family member or a close friend; or learning that one's child has a life threatening disease.  The disorder may be especially sever or long lasting when the stressor is of human design (e.g., torture, rape). the likelihood of developing this disorder may increase as the intensity of and physical proximity to the stressor increase.

The traumatic event can be re-experienced in various ways.  Commonly the person has recurrent and intrusive recollections of the event (Criterion B1) or recurrent distressing dreams during which the event can be replayed or otherwise represented (Criterion B2). In rare instances, the person experiences dissociative states that last from a few seconds to several hours, or even days, during which components of the event are relived and the person behaves as though experiencing the event at that moment (Criterion B3).  These episodes, often referred to as "flashbacks," are typically brief but can be associated with prolonged distress and heightened arousal.  Intense psychological distress (Criterion B4) or physiological reactivity (Criterion B5) often occurs when the person is exposed to triggering events that resemble or symbolize an aspect of the traumatic event (e.g., anniversaries of the traumatic event; cold, snowy weather or uniformed guards for survivors of death camps in cold climates; hot, humid weather for combat veterans of the South Pacific; entering any elevator for an woman who was reaped in an elevator).

Stimuli associated with the trauma are persistently avoided.  The person commonly makes deliberate efforts to avoid thoughts, feelings, or conversations about the traumatic event (Criterion C1) and to avoid activities, situations, or people who around recollections of it (Criterion C2).  This avoidance of reminders may include amnesia for an important aspect of the traumatic event (Criterion C3).  Diminished responsiveness to the external work, referred to as "psychic numbing" or "emotional anesthesia," usually begins soon after the traumatic event.  The individual may complain of having markedly diminished interest or participation in previously enjoyed activities (Criterion C4), of feeling detached or estranged from other people (Criterion C5), or of having markedly reduced ability to feel emotions (especially those associated with intimacy, tenderness and sexuality) (Criterion C6).  The individual may have a sense of a foreshortened future (e.g., not expecting to have a career, marriage, children, or a normal life span) (Criterion C7).

The individual has persistent symptoms of anxiety or increased arousal that were not present before the trauma.  these symptoms may include difficulty falling or staying asleep that may be to recurrent nightmares during which the traumatic event is relived (Criterion D1), hypervigilance (Criterion D4), and exaggerated startle response (Criterion D5).  Some individuals report irritability or outburst of anger (Criterion D2) or difficulty concentrating or completing tasks (Criterion D3)."

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Dissociative Identity Disorder (DID)

"The essential feature of Dissociative identity Disorder is the presence of two or more distinct identities or personality states (Criterion A) that recurrently take control of behavior (Criterion B).  There is an inability to recall important personal information, the extent of which is too great to be explained by ordinary forgetfulness (Criterion C).  The disturbance is not due tot eh direct physiological effects of a substance or a general medical condition (Condition D.).  In children, the symptoms cannot be attributed to imaginary playmates or other fantasy play.

Dissociative Identity Disorder reflects a failure to integrate various aspects of identity, memory, and consciousness.  Each personality state may be experienced as if it has a distinct personal history, self-image, and identity, including a separate name.  Usually there is a primary identity that carries the individual's given name and is passive, dependent, guilty, and depressed.  The alternate identities frequently have different names and characteristics that contrast with the primary identity (e.g., are hostile, controlling, and self-destructive).  Particular identities may emerge in specific circumstances and may differ in reported age and gender, vocabulary, general knowledge, or predominant affect.  Alternate identities are experienced as taking control in sequence, ore at the expense of the other, and may deny knowledge of one another, be critical of one another, or appear to be in open conflict.  Occasionally, one or more powerful identities allocate time to the others.  Aggressive or hostile identities may at times interrupt activities or place the others in uncomfortable situations.

Individuals with this disorder experience frequent gaps in memory for personal history, both remote and recent.  The amnesia is frequently asymmetrical.  The more passive identities tend to have more constricted memories, whereas the more hostile, controlling, or "protector" identities have more complete memories.  An identity that is not in control may nonetheless gain access to consciousness by producing auditory or visual hallucinations (e.g., a voice giving instructions).  Evidence of amnesia may be uncovered by reports from others who have witnessed behavior that is disavowed by the individual or by the individual's own discoveries (e.g., finding items of clothing at home that the individual cannot remember having bought).  There may be loss of memory not only for recurrent periods of time, but also an overall loss of biographical memory for some extended period of childhood, adolescence, or even adulthood.  Transitions among identities are often triggered by psychosocial stress.  The time required to switch from one identity to another is usually a matter of seconds, but, less frequently, may b gradual.  Behavior that may be frequently associated with identity switches include rapid blinking, facial changes, changes in voice or demeanor, or disruption in the individual's train of thoughts.  The number of identities reported ranges from 2 to more than 100.  Half of reported cases include the individuals with 10 or fewer identities."

Diagnostic and Statistical Manual of Mental Disorders. 2000.  4th ed. Washington, D.C.: American Psychiatric Association.

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Life Cycle Journeys Contents

    

 

Table of Contents

 

   

Bipolar Disorder and Trauma

Title: Psychological Trauma and the Borderline Personality.
Author(s): Everly, George S. Jr. , Loyola College, MD, US; Lating, Jeffrey M. , Loyola College, MD, US
Source: Everly, George S. Jr.; Lating, Jeffrey M.; 2004.
Personality-guided therapy for posttraumatic stress disorder.
Personality-guided psychology. Washington, DC, US: American
Psychological Association. pp. 197-208
Abstract: The purpose of this brief review was to examine the
association between trauma, posttraumatic stress disorder, and the occurrence of bipolar disorder.                                   _____

Title: Childhood trauma and hallucinations in bipolar affective
disorder: Preliminary investigation.
Author(s): Hammersley, Paul ,
Paul@hammersley7616.freeserve.co.uk,
U Manchester, Dept of Psychology, Manchester, England; Dias, Anton, South Staffs Mentally Disordered Offenders Team, St.
George's Hospital, Stafford, United Kingdom; Todd, Gillian, Barton House Clinic, Addenbrookes Hospital, Cambridge, United Kingdom; Bowen-Jones, Kim, Trengweth Mental Health Unit, Redruth, United Kingdom; Reilly, Bernadette, Dept of Psychological Medicine, Gartnavel Royal Hospital, Glasgow, United Kingdom; Bentall, Richard P. , U Manchester, Dept of Psychology, Manchester, England
Source: British Journal of Psychiatry, Vol 182(6), Jun 2003.
pp. 543-547.
Publisher: United Kingdom: Royal College of Psychiatrists.
Abstract: Strong evidence exists for an association between
childhood trauma, particularly childhood sexual abuse, and
hallucinations in schizophrenia. Hallucinations are also well-documented symptoms in people with bipolar affective disorder. The aim of this study was to investigate the relationship between childhood sexual abuse and other childhood traumas and hallucinations in people with bipolar affective disorder. A sample of 96 participants (aged 22-70 yrs) was drawn from the Medical Research Council multicentre trial of cognitive
behavioural therapy for bipolar affective disorder. The trial therapists recorded spontaneous reports of childhood sexual abuse made during the course of therapy. Symptom data were collected by trained research assistants masked to the hypothesis. A significant association was found between those reporting general trauma (n=38) and auditory
hallucinations. A highly significant association was found between those reporting childhood sexual abuse (n=15) and auditory hallucinations. The relationship between childhood sexual abuse and hallucinations in bipolar disorder warrants further investigation.
  _____

Title: Transtorno de estresse pos-traumatico e transtorno de humor bipolar.
Translated Title: Posttraumatic stress disorder and bipolar mood disorder.
Author(s): Vieira, Rodrigo Machado,
rvieira@usp.br, Programa de Transtorno de Humor Bipolar do Hospital de Clinicas de Porto
Alegre-UFRGS, Porto Alegre, Brazil; Gauer, Gabriel J. C., Departamento de Psiquiatria e Medicina Legal e do Programa de Mestrado em Ciencias Criminais da PUCRS, Brazil
Source: Revista Brasileira de Psiquiatria , Vol 25(Suppl1), Jun
2003. pp. 55-61.
Publisher: Brazil: Associacao Brasileira de Psiquiatria.
Abstract: Bipolar disorder (BD) is not only an endogenous
condition. Severe negative life events have been shown to influence the development of the first episode and lifetime course of BD.  Posttraumatic stress disorder (PTSD) is a severe and incapacitating mental condition that affects a significant proportion of the general population at some time in their lives. The concomitant presence of BD and PTSD has been shown to be more frequent than previously suggested and psychotic patients with trauma histories have a tendency to present
more severe symptoms and are more prone to present substance use disorders. Trauma-related intrusive memories and nightmares of PTSD have been associated with mood changes. Also, kindling and behavioral sensitization have been proposed to explain the etiology and course of both disorders. Pharmacological approaches for this comorbidity are
still based on empirical or not controlled approaches. In this article, we critically review the current literature regarding this comorbid condition, and highlight some aspects related to epidemiology, etiology, course and pharmacological treatment of both disorders. Overall, our review emphasizes the importance of systematically evaluating trauma histories in patients with BD.
  _____

Title: Childhood abuse, depression, and anxiety in adult psychiatric outpatients.
Author(s): Gibb, Brandon E. ,
bgibb@binghamton.edu, Binghamton U, Dept of Psychology, Binghamton, NY, US; Butler, Andrew C. , Beck Inst for Cognitive Therapy & Research, Bala Cynwyd, PA, US; Beck, Judith S. , Beck Inst for Cognitive Therapy & Research, Bala Cynwyd, PA, US
Source: Depression & Anxiety , Vol 17(4), 2003. pp. 226-228.
Publisher: US: John Wiley & Sons.
Abstract: Examined the relation between 522 adult psychiatric
outpatients' reports of childhood emotional, physical, and sexual abuse and their current symptoms and diagnoses of depression and anxiety. Ss were diagnosed with major depression, dysthymia, generalized anxiety disorder, panic disorder, bipolar disorder, or substance dependence. Ss
provided information on childhood emotional, physical, and sexual abuse. Reports of childhood emotional abuse were more strongly related to their symptoms and diagnoses of depression than anxiety. Reports of physical abuse were more strongly related to symptoms of anxiety than depression.  Reports of sexual abuse were equally strongly related to symptoms and
diagnoses of depression and anxiety.
  _____

Title: Traumatic grief treatment: Case histories of 4 patients.
Author(s): Harkness, Kate L., U Pittsburgh, Medical Ctr, Western Psychiatric Inst & Clinic, Anxiety Disorders Prevention Program, Pittsburgh, PA, US; Shear, M. Katherine , U Pittsburgh, Medical Ctr, Western Psychiatric Inst & Clinic, Anxiety Disorders Prevention Program, Pittsburgh, PA, US; Frank, Ellen , U Pittsburgh, Medical Ctr, Western Psychiatric Inst & Clinic, Anxiety Disorders Prevention Program, Pittsburgh, PA, US; Silberman, Rebecca A. , U Pittsburgh, Medical Ctr, Western Psychiatric Inst & Clinic, Anxiety Disorders Prevention Program, Pittsburgh, PA, US
Source: Journal of Clinical Psychiatry , Vol 63(12), Dec 2002.
pp. 1113-1120.
Publisher: US: Physicians Postgraduate Press.
Abstract: Traumatic grief treatment (TGT) is a newly developed intervention for a debilitating bereavement-related condition. TGT uses imaginal and in vivo exposure techniques to target emotional distress and behavioral avoidance hypothesized to be core features of the syndrome, along with interpersonal psychotherapy techniques to engage patients and maintain rapport. The present report describes 4 case
histories of patients treated in this way. Each patient met our
criterion for traumatic grief, defined as a score of at least 25 on the Inventory of Complicated Grief. Additionally, all 4 patients met DSM-IV criteria for a current episode of major depression and 1 patient for bipolar II disorder. The treatment course followed a direct replication design and ranged from 14 to 18 weekly 60- to 90-minute sessions. These 4 cases illustrate reduction in distress during exposure to painful
emotional memories and avoided situations that was associated with decreased scores on measures of traumatic grief, depression, and anxiety and increased participation in and enjoyment of daily-life activities. Case histories of TGT suggest it is a promising treatment for individuals suffering from traumatic grief. It appears that imaginal reliving and in vivo exposure are effective in reducing grief intensity.
  _____

Title: Trauma exposure and posttraumatic stress disorder in psychosis: Findings from a first-admission cohort.
Author(s): Neria, Yuval , State U of New York at Stony Brook, Dept of Psychiatry & Behavioral Science, US; Bromet, Evelyn J.; Sievers, Sylvia; Lavelle, Janet; Fochtmann, Laura J.
Source: Journal of Consulting & Clinical Psychology , Vol 70(1),
Feb 2002. pp. 246-251.
Publisher: US: American Psychological Assn.
Abstract: This study examined the lifetime prevalence of trauma exposure and posttraumatic stress disorder (PTSD) and their demographic, diagnostic, and trauma-related correlates in a clinical cohort of 426 patients with a first psychiatric admission for psychosis. The prevalence of trauma exposure was 68.5%. Female gender and substance abuse were risk factors for trauma exposure. The prevalence of PTSD was
14.3% in the full sample and 26.5% in those with trauma exposure. PTSD was less prevalent in patients with bipolar disorder and schizophrenia and was twice as common in women. Other significant risk factors were younger age and trauma exposure that was repeated and ongoing or that
involved childhood victimization. The findings highlight the importance of systematically ascertaining trauma histories in patients with psychotic disorders.
  _____

Title: On the epidemiology of posttraumatic stress disorder: Period prevalence rates and acute service utilization rates among Massachusetts Medicaid program enrollees: 1993--1996.
Author(s): Macy, Robert Donnelly , Union Inst And U., US
Source: Dissertation Abstracts International: Section B: The
Sciences & Engineering , Vol 63(6-B), Jan 2002. pp. 3014.
Publisher: US: Univ Microfilms International.
Abstract: Period prevalence rates of DSM III-R posttraumatic
stress disorder (PTSD) were studied in the statewide Massachusetts Medicaid Mental Health and Substance Abuse Program. Among 85,000 enrolled Medicaid recipients seeking treatment, 55,931 received one of the five study diagnoses that included PTSD, Panic Disorder, Multiple Personality Disorder, Major Depression, and Bipolar Disorder.
Interactions between period prevalence rates by study diagnoses, gender, multiple age and public assistance AID categories, and acute service utilization rates were investigated. Major Depression (n = 21,842) ranked highest with an overall period prevalence rate of 390.5 per 1,000
(CI: 386.5-394.6). PTSD (n = 19,775) ranked second highest with an overall period prevalence rate of 353.6 per 1000 (CI: 346.6-357.5). PTSD exhibited its highest period prevalence rate, 609.5 per 1,000 (CI: 601.0-618.0), for the study population in the youngest age group (5 to 12 years). Age-specific PTSD period prevalence rates for both the youngest age group and the aggregate of the two youngest age groups (5 to 18 years) far exceed rates in both the other study diagnoses, and in all of the published rates for comparable child treatment seeking populations. PTSD ranked highest for utilization of acute inpatient days and for length of stay and ranked highest in overall cost for acute service utilization. The highest PTSD period prevalence rates were positively associated with the AID category of refugee, orphans and children under 21 in need of medical assistance. This study may provide a unique first look at age-specific PTSD period prevalence rates for non-disaster youth populations, and certainly argues for further investigation among community treatment seeking samples into the positive associations between age, trauma exposure and the early development of PTSD.
  _____

Title: Atesli silah yaralanmasini takiben duygudurum bozuklugu: Bir olgu sunumu.
Translated Title: Mood disorder following gun shot: A case
presentation.
Author(s): Guelpek, Demet , Ege U, Tip Fakueltesi Psikiyatri AD, Bornova-IZMIR, Turkey; Bora, Emre , Ege U, Tip Fakueltesi Psikiyatri AD, Bornova-IZMIR, Turkey; Bayraktar, Erhan , Ege U, Tip Fakueltesi Psikiyatri AD, Bornova-IZMIR, Turkey
Source: Klinik Psikofarmakoloji Buelteni , Vol 12(1), 2002. pp.
26-30.
Publisher: Turkey: Kure Iletisim Grubu AS.
Abstract: Secondary mood disorders are a well known consequence of head trauma. Although self-limiting mania following head trauma is also relatively common, bipolar mania is much more rare. The authors discuss a case of secondary mood disorder following a gun shot to the head.  Magnetic resonance imaging (MRI) revealed a gross right basotemporal
cortex lesion and corticosubcortical atrophy. Neuropsychological evaluation revealed an apparent visual memory loss and frontosubcortical dysfunction. This case may help to clarify the biological mechanisms underlying bipolar disorder.
  _____

Title: Antiepileptic drugs and agents that inhibit voltage-gated sodium channels prevent NMDA antagonist neurotoxicity.
Author(s): Farber, N. B. ,
farbern@psychiatry.wustl.edu, Department of Psychiatry, Washington University, St Louis, MO, US; Jiang, X.-P. , Department of Psychiatry, Washington University, St Louis, MO, US; Heinkel, C. , Department of Psychiatry, Washington University, St Louis, MO, US; Nemmers, B. , Department of Psychiatry, Washington University, St Louis, MO, US
Source: Molecular Psychiatry , Vol 7(7), 2002. pp. 726-733.
Publisher: United Kingdom: Nature Publishing.
Abstract: N-methyl-D-aspartate (NMDA) glutamate receptor
antagonists are used in clinical anesthesia and are being developed as therapeutic agents for preventing neurodegeneration in stroke, epilepsy, and brain trauma. However, the ability of these agents to produce
neurotoxicity in adult rats and psychosis in adult humans compromises their clinical usefulness. In addition, an NMDA receptor hypofunction (NRHypo) state might play a role in neurodegenerative and psychotic disorders, like Alzheimer's disease, bipolar disorder and schizophrenia. Thus, developing pharmacological means of preventing these
NRHypo-induced effects could have significant clinically relevant benefits. NRHypo neurotoxicity appears to be mediated by a complex disinhibition mechanism that results in the excessive stimulation of certain vulnerable neurons. Here we report our findings that five agents thought to possess anticonvulsant activity because they inhibit voltage-gated sodium channels, prevent NRHypo neurotoxicity. We also
found that three other anticonvulsants, whose mechanism is less clear, also prevent NRHypo neurotoxicity, suggesting that inhibition of voltage-gated sodium channels is not the only mechanism via which anticonvulsants can act to prevent NRHypo neurotoxicity.
  _____

Title: Karthikaya: The boy who wished to be Shiva: Case study of an Indian cultural dynamic.
Author(s): Guzder, Jaswant , McGill U, Dept of Psychiatry,
Montreal, PQ, Canada
Source: Azima, Fern J. Cramer (Ed); Grizenko, Natalie (Ed);
2002. Immigrant and refugee children and their families: Clinical,
research, and training issues. Madison, CT, US: International
Universities Press, Inc. pp. 65-91
Abstract: The case study presented in this chapter involves an Indian Hindu family migrating to Canada within a year after the death of the father who had suffered recurrent episodes of bipolar disorder. The 10-yr-old patient presented to the emergency room as a distressed school phobic boy. He could be diagnosed as a child with overanxious disorder or posttraumatic stress disorder, or might be considered at high risk later for bipolar disorder. The chapter provides an account of treatment intervention and nontreatment as the case evolved over 2 yrs, and discusses how transcultural dilemmas and interpretations became significant to his mastery of trauma and identity issues. The author notes that the course of clinical interventions and outcome for this family's migration experience allows for reflection upon the complex intermingling of universal versus culturally specific dimensions of the clinical encounters.
  _____

Title: Thrombosis associated with physical restraints.
Author(s): Hem, E., U Oslo, Dept of Behavioural Sciences in
Medicine, Oslo, Norway; Steen, O.; Opjordsmoen, S.
Source: Acta Psychiatrica Scandinavica, Vol 103(1), Jan 2001. pp. 73-76.
Publisher: US: Munksgaard Scientific Journals.
Abstract: Described two cases of thromboembolic phenomena, one with a fatal outcome, in association with physical restraint during admission to an emergency psychiatric ward. The thromboembolic phenonema were diagnosed in a 29 yr old man with exacerbated chronic paranoid schizophrenia, who was restrained due to physical agitation, and in a 59 yr old man with bipolar 1 disorder, most recent episode manic, who was
admitted because of severe physical agitation and later collapsed following release from his restraints. A search of the world literature showed no papers on thrombosis in physical restraint. It is concluded that immobilization and trauma to the legs while restraining a patient are adequate explanations for the occurrence of thrombosis. Special attention should be paid to thrombosis when employing restraints in psychiatric wards. Further systematic research into physical restraints in psychiatry is clearly needed. A comment by D. Moussaoui is included.
  _____

Title: Pediatric mania: A developmental subtype of bipolar disorder?
Author(s): Biederman, Joseph , Massachusetts General Hosp,
Pediatric Psychopharmacology Unit, Boston, MA, US; Mick, Eric; Faraone, Stephen V.; Spencer, Thomas; Wilens, Timothy E.; Wozniak, Janet
Source: Biological Psychiatry , Vol 48(6), Sep 2000. Special
Issue: A special issue on bipolar disorder. pp. 458-466.
Abstract: Reviews and integrates the existing literature on
pediatric mania into a conceptual framework to understand historical misdiagnosis. Despite ongoing controversy, the view that pediatric mania is rare or nonexistent has been increasingly challenged not only by case reports, but also by systematic research. This research strongly suggests that pediatric mania may not be rare but that it may be difficult to diagnose. Since children with mania are likely to become
adults with bipolar disorder, the recognition and characterization of childhood-onset mania may help identify a meaningful developmental subtype of bipolar disorder worthy of further investigation. The major difficulties that complicate the diagnosis of pediatric mania include: 1) its pattern of comorbidity may be unique by adult standards, especially its overlap with attention-deficit/hyperactivity disorder,
aggression, and conduct disorder; 2) its overlap with substance use disorders; 3) its association with trauma and adversity; and 4) its response to treatment is atypical by adult standards.
  _____

Title: Psychiatric morbidity and comorbidity following accidental
man-made traumatic events: Incidence and risk factors.
Author(s): Maes, Michael , U Hosp of Maastricht, Dept of Psychiatry & Neurology, Maastricht, Netherlands; Mylle, Jacques; Delmeire, Laure; Altamura, Carlo
Source: European Archives of Psychiatry & Clinical Neuroscience, Vol 250(3), 2000. pp. 156-162.
Publisher: Germany: Springer Verlag.
Abstract: The aims of this study were to examine the incidence and risk factors of major depression, bipolar disorder, psychoactive substance abuse, psychotic, and anxiety disorders in relation to posttraumatic stress disorder (PTSD) in a study group exposed to 2 different traumatic events, i.e. 128 fire and 55 motor vehicle accident victims. Data have been collected 7-9 mo after the traumatic event. The diagnosis of axis-I diagnoses, other than PTSD, was made according to
Diagnostic and Statistical Manual of Mental Disorders-III-Revised (DSM-III-R) criteria using the Structured Interview according to DSM-III-R. The incidence of new-onset major depression was 13.4%, generalized anxiety disorder 12.6%, agoraphobia 10.2%, and psychoactive substance use disorders 6%. Simple phobia, panic disorder, and obsessive
compulsive disorder had much lower incidence. 51 percent of the victims with PTSD had 1 or more additional axis-I diagnoses, major depression (26.2%), agoraphobia (21.0%), and generalized anxiety disorder (24.6%) being the most common. Physical injury was the single best predictor for
major depression. The best predictors for the development of new-onset anxiety disorders, other than PTSD, were: type and horror of trauma, the extent of physical injury, the loss of control during the traumatic event, contextual stimuli, younger age, and female sex.
  _____

Title: Correlation between childhood bipolar I disorder and reactive attachment disorder, disinhibited type.
Author(s): Alston, John F., Private Practice, Evergreen, CO, US
Source: Levy, Terry M. (Ed); 2000. Handbook of attachment
interventions. San Diego, CA, US: Academic Press, Inc. pp. 193-242
Abstract: Describes, from substantial clinical experience, a new conceptualization of the role that mood disorders, specifically bipolar disorder, play in the lives of maltreated children who subsequently develop associated emotional and behavioral problems relating to bonding and attachment. This conceptualization takes both trauma and attachment
theories into account and is not in opposition to them, but offers different perspectives in reaching certain conclusions. Based on clinical experience, the author describes the psychiatric diagnoses of abusive parents that are indicators of genetic vulnerability for the development of mood disorders in maltreated children; presents differential characteristics of attention deficit disorder, bipolar disorder, and reactive attachment disorder, disinhibited type; and reviews effective medical treatment plans, specifically addressing medications useful in the psychopharmacology of disruptive behavioral
disorders associated with early-life maltreatment. Recognition of the correlations between bipolar disorder and reactive attachment disorder, disinhibited type leads to more effective treatment plans, resulting in greater emotional accessibility and receptivity, social reciprocity, self control, and improved mood and self-esteem.
  _____

Title: Elation, mania, and mood disorders: Evidence from neurological disease.
Author(s): Robinson, Robert G., U Iowa, Coll of Medicine, Dept of Psychiatry, Iowa City, IA, US; Manes, Facundo  Source: Borod, Joan C. (Ed); 2000. The neuropsychology of emotion. Series in affective science. London: Oxford University Press. pp. 239-268
Abstract: There have been 2 primary lines of thought in the study of emotional disorders that are associated with structural brain disease. One attributes mood disorders to an understandable psychological reaction to the associated impairment; the other, based on a lack of association between severity of impairment and severity of emotional disorder, suggests a direct causal connection between emotional disorders and structural brain damage.  Topics include:
elation and mania associated with stroke (relationship to lesion
location, risk factors for mania following stroke, mechanism,
treatment); mania associated with traumatic brain injury (prevalence, relationship to impairment variables, relationship to lesion location, mechanism); bipolar disorder associated with stroke or trauma; depression associated with stroke (longitudinal course of depression, relationship to impairment, relationship to lesion location, comparison of cortical and subcortical lesions in the production of post-stroke mood disorders, mechanism of depression following stroke, treatment of depression following stroke); depression associated with Parkinson's disease (prevalence, relationship to cognitive impairment, mechanism, treatment); and depression associated with traumatic brain injury.
  _____

Title: The creative matrix: Anxiety and the origin of creativity.
Series Title: The reshaping of psychoanalysis; vol. 10.
Author(s): Brink, Andrew
Source: 2000. New York, NY, US: Peter Lang Publishing, Inc..
vii, 221 pp.
Abstract: This book shows how Freudian and Kleinian theories of creativity are giving way to an attachment model, owing to research on anxiety by J. Bowlby and other psychobiologists. We are entering an era of rapproachment between psychoanalysis, neurobiology, and attachment theory. Theory of creativity must take into account the rapid advances
toward an integrated view of human development and capacity for adaptation. This book offers a critical review of British Object Relations theories of creativity from M. Klein through R. Fairbairn, M. Milner, D. W. Winnicott, and others. It studies these theories in light of Bowlby's challenge to psychoanalytic accounts of child development and personality formation. Creativity is seen as a necessary concomitant of anxious attachment in infants and children--as a natural adaptive
resource in overcoming trauma and other deflections of normal
development. Brief studies of poets R. Lowell, S. Plath, and A. Sexton show how attachment theory illuminates bipolar disorder and poetic creativity.
Table of Contents: Acknowledgments
Introduction: The creative matrix
Part I: Central concepts
..Anxiety, adaptation and fear
..The biology of regeneration
..Regeneration and communication
Part II: A review of psychoanalytic theories of creativity
..Sigmund Freud and Otto Rack on creativity
..Melanie Klein and reparation
..Ronald Fairbairn: Beyond "restitution"
..D. W. Winnicott as tiresias
..Adrian Stokes: Aesthetics, eros and death
..Marion Milner: Psychoanalysis and contemplative creativity
..Alice Miller: Creativity as insight
Part III: Creativity: The manic-depression controversy
..Nancy C. Andreasen, Kay R. Jamison and others: Studies of creativity
..Three bipolar poets reconsidered: Robert Lowell, Anne Sexton and Sylvia Plath
Conclusion: Attachment, trauma and a new view of creativity
Bibliography
Name index
  _____

Title: Traumatic brain injury in individuals convicted of sexual
offenses with and without bipolar disorder.
Author(s): DelBello, Melissa P. , U Cincinnati, Coll of Medicine,
Dept of Psychiatry, Bipolar & Psychotic Disorders Research & Biological Psychiatry Programs, Cincinnati, OH, US; Soutullo, Cesar A.; Zimmerman, Molly E.; Sax, Kenji W.; Williams, Jamie R.; McElroy, Susan L.; Strakowski, Stephen M.
Source: Psychiatry Research , Vol 89(3), Dec 1999. pp. 281-286.
Publisher: US: Elsevier Scientific.
Abstract: Examined the occurrence of traumatic brain injury (TBI) in individuals convicted of sexual offenses with (n = 9) and without (n = 16) bipolar disorder and a comparison group of 15 patients with bipolar disorder without a history of sexual offending behaviors. Individuals convicted of sexual offenses and diagnosed with bipolar disorder had greater rates of brain injury resulting from head trauma than individuals convicted of sexual offenses without bipolar disorder and comparison patients with bipolar disorder. TBI predated the first
sexual offense and/or the onset of bipolar disorder in most Ss.
  _____

Title: Reliability of reports of violent victimization and
posttraumatic stress disorder among men and women with serious mental illness.
Author(s): Goodman, Lisa A., Boston Coll, School of Education,
Counseling Psychology Program, Boston, MA, US; Thompson, Kim M.; Weinfurt, Kevin; Corl, Susan; Acker, Pat; Mueser, Kim T.; Rosenberg, Stanley D.
Source: Journal of Traumatic Stress , Vol 12(4), Oct 1999. pp.
587-599.
Publisher: US: Kluwer Academic/Plenum Publishers.
Abstract: Although violent victimization is highly prevalent among men and women with serious mental illness (SMI, e.g., schizophrenia, bipolar disorder), future research in this area may be impeded by controversy concerning the ability of individuals with SMI to report traumatic events reliably. This article presents the results of a study exploring the temporal consistency of reports of childhood sexual abuse, adult sexual abuse, and adult physical abuse, as well as current
symptoms of posttraumatic stress disorder (PTSD) among 50 people with SMI (29 women whose mean age was 42.1 yrs and 21 men with a mean age of 37.6). Results show that trauma history and PTSD assessments can, for the most part, yield reliable information essential to further research in this area. The study also demonstrates the importance of using a
variety of statistical methods to assess the reliability of self-reports of trauma history.
  _____

Title: Categorizing fear: The role of trauma in a clinical formulation.
Author(s): Burton, John K. , Columbia U, Coll of Physicians &
Surgeons, Dept of Psychiatry, New York, NY, US; Marshall, Randall D.
Source: American Journal of Psychiatry , Vol 156(5), May 1999. pp. 761-766.
Publisher: US: American Psychiatric Assn.
Abstract: Illustrates, in a case report, the difficulties that can
accompany the evaluation and treatment of an individual with a history of severe psychological trauma, who meets criteria for several disorders, and presents problems in multiple domains of functioning. The social, family and psychiatric history of a 39-yr old female is presented, followed by evaluation information. Problems in treatment are highlighted including split psychotherapy and pharmacotherapy treatments following initial diagnoses of bipolar disorder and borderline
personality disorder. The patients' affective lability and trauma and abuse history are focused upon in relation to a subsequent diagnostic formulation of PTSD, chronic; dissociative disorder; major depressive disorder, recurrent, and personality disorder.
  _____

Title: Possible gabapentin-induced thyroiditis.
Author(s): Frye, Mark A. , U California, Psychiatric Inst, Los
Angeles, CA, U; Luckenbaugh, Dave; Kimbrell, Tim A.; Constantino, Cassandra; Grothe, Dale; Cora-Locatelli, Gabriela; Ketter, Terence A.
Source: Journal of Clinical Psychopharmacology , Vol 19(1), Feb 1999. pp. 94-95.
Publisher: US: Lippincott Williams & Wilkins.
Abstract: Presents the case of a possible association between
gabapentin and thyroiditis. The patient, a 28-yr-old nonsmoking female with rapid cycling bipolar II disorder, had a medical history notable for atypical tuberculosis, epiglottis, and right frontal head trauma without loss of consciousness as a child. Over a course of 5 mo, the S participated in a randomized, double-blind, crossover trial of gabapentin monotherapy vs lamotrigine monotherapy vs placebo. After this study period, she began a blinded combination phase of both
anticonvulsants. Thyroid function was assessed twice monthly. Her baseline thyroid function was normal, as was her serum thyroglobulin level. During the midphase of gabapentin, 3,600 mg/day, she was noted to be only mildly depressed. However, over the next several weeks during which she received a higher dose of gabapentin (4,800 mg), she developed mild physical symptoms of hyperthyroidism. Mood instability was also
present. Her vital signs were stable, and physical examination findings were negative for exophthalmus, enlarged thyroid gland, or hyperreflexia. Upon gabapentin discontinuation there was prompt resolution of symptoms and a return to baseline thyroid function. Thus, a provisional diagnosis of a gabapentin-induced thyroiditis was made.                        _____

Title: Antecedents and complications of trauma in boys with ADHD: Findings from a longitudinal study.
Author(s): Wozniak, Janet , Massachusetts General Hosp, Pediatric Psychopharmacology Unit, Boston, MA, US; Crawford, Margaret Harding; Biederman, Joseph; Faraone, Stephen V.; Spencer, Thomas J.; Taylor, Andrea; Blier, Heather K.
Source: Journal of the American Academy of Child & Adolescent Psychiatry , Vol 38(1), Jan 1999. pp. 48-56.
Publisher: US: Lippincott Williams & Wilkins.
Abstract: Examined the relationship between trauma and
attention-deficit hyperactivity disorder (ADHD) and evaluated whether ADHD increases the risk for trauma, the risk for posttraumatic stress disorder (PTSD), or the risk for trauma-associated psychopathology. Data from a longitudinal sample of 260 male children and adolescents (aged 6-17 yrs) with and without ADHD were examined. All were evaluated comprehensively with assessments in multiple domains of functioning including systematic assessments of trauma and PTSD. Comparisons were made between traumatized and nontraumatized youths with and without ADHD. No meaningful differences were detected in comparisons between ADHD and control children, either in the rate of trauma exposure or in
the development of PTSD. Although trauma was associated with the development of major depression, this effect was independent of ADHD status. In contrast, bipolar disorder at baseline assessment was a significant risk factor for subsequent trauma exposure.
  _____

Title: Frequently missed diagnoses in adolescent psychiatry.
Author(s): Berenson, Claudia K., U New Mexico, Health Sciences Ctr, Dept of Psychiatry, Albuquerque, NM, US
Source: Psychiatric Clinics of North America, Vol 21(4), Dec
1998. pp. 917-926.                                                  Publisher: US: WB Saunders.
Abstract: Symptom overlap, comorbidity, disagreement among
informants, and the impact of development complicate psychiatric diagnoses in the adolescent patient. The authors review frequently missed diagnoses including anxiety disorders, attention deficit disorder without hyperactivity, early-onset bipolar disorder, syndromes associated with trauma, and substance abuse.
  _____

Title: What are the effects of homelessness on children socially, educationally, and emotionally?
Author(s): Anglin, Beryl Fletcher , The Union Inst, US
Source: Dissertation Abstracts International Section A:
Humanities & Social Sciences , Vol 59(3-A), Sep 1998. pp. 0722.
Publisher: US: University Microfilms International.
Abstract: This Project Demonstrating Excellence (PDE) dissertation came about as a result of months of studying homeless children, their families, 10 educators and 10 advocates for the homeless. The study concentrated on the personal stories and experiences of the homeless
participants who were from different races. It focused on why these families became homeless and how they are coping with homelessness. The study emphasized the necessity for coordination and collaboration among private and public agencies. The question that directed this inquiry is:
What are the Effects of Homelessness on Children Socially,
Educationally, and Emotionally? The question illicits a broad and clear picture that a number of the participants suffered from bronchitis, asthma, bipolar disorder, skin rashes and emotional traumas as a direct result of their homelessness. A series of economic hardships, substance abuse, a shortage of low-income housing, divorce, physical and mental abuse, lack of marketable skills and psychological traumas are some of
the causes of their homeless according to the findings of this study. The study showed that misconceptions about the homeless are common. (Bassuk, 1996) concurs with my findings that the explosion of homelessness has now surpassed the ability of local governments and charities to deal with the problem. Relevant to the study is the isolation in which homeless people exist, and the fact that homeless
children are compelled to change shelters and schools several times during any one year because of the instability of homelessness. The study found that homeless children never stay in one place long enough to attain a sense of belonging. Because homeless children need much love, acceptance and understanding, schools must change the way they function in order to provide acceptance and a sense of belonging for
them. The code of silence that surrounds homeless children must be broken so that educators can be better able to service their needs. The research reveals what it means to be homeless and how so many people have come to such impasse in their young lives.
  _____

Title: Trauma and posttraumatic stress disorder in severe mental illness.
Author(s): Mueser, Kim T. , New Hampshire--Dartmouth Psychiatric Research Ctr, Concord, NH, US; Goodman, Lisa B.; Trumbetta, Susan L.; Rosenberg, Stanley D.; Osher, Fred C.; Vidaver, Robert; Auciello, Patricia; Foy, David W.
Source: Journal of Consulting & Clinical Psychology, Vol 66(3),
Jun 1998. pp. 493-499.
Publisher: US: American Psychological Assn.
Abstract: This research assessed the lifetime prevalence of
traumatic events and current posttraumatic stress disorder (PTSD) in 275 patients with severe mental illness (e.g., schizophrenia and bipolar disorder) receiving public mental health services in Concord and Manchester, New Hampshire and Baltimore, Maryland. Lifetime exposure to traumatic events was high, with 98% of the sample reporting exposure to at least 1 traumatic event. The rate of PTSD in our sample was 43%, but
only 3 of 119 patients with PTSD (2%) had this diagnosis in their charts. PTSD was predicted most strongly by the number of different types of trauma, followed by childhood sexual abuse. The findings suggest that PTSD is a common comorbid disorder in severe mental illness that is frequently overlooked in mental health settings.
  _____

Title: Plasma dopamine beta-hydroxylase activity in psychotic and non-psychotic post-traumatic stress disorder.
Author(s): Hamner, Mark B. , Ralph H. Johnson Veterans Affairs Medical Ctr, Mental Health Services, Charleston, SC, US; Gold, Paul B.
Source: Psychiatry Research, Vol 77(3), Feb 1998. pp. 175-181.
Publisher: US: Elsevier Scientific.
Abstract: Altered dopamine beta-hydroxylase (DBH) activity has been reported in mood disorders. Plasma DBH is reduced in major depression with psychosis and elevated in bipolar disorder with psychosis compared with their respective non-psychotic diagnostic groups. The authors therefore evaluated DBH activity in posttraumatic stress disorder (PTSD) patients with and without psychotic features and compared these groups with age- and gender-matched control Ss. 19 male Vietnam combat veterans (aged 41-60 yrs) with PTSD (including patients with and without psychotic features) had plasma DBH enzyme activity assayed photometrically. DBH was significantly higher in patients with PTSD with psychotic features than in patients without psychotic features and was also higher than that in normal control Ss. It is concluded that plasma DBH activity may differentiate psychotic and non-psychotic
subtypes of PTSD. The observed changes are opposite to those seen in psychotic depression but comparable to psychotic bipolar disorder. Since DBH is a genetic marker, this may reflect individual vulnerabilities to develop psychosis in the context of trauma.
  _____

Title: Psychotherapy.
Author(s): McAlpin, Charlene A., U Miami, Jackson Memorial Medical Ctr, Coral Gables, FL, US; Goodnick, Paul J.
Source: Goodnick, Paul J. (Ed); 1998. Mania: Clinical and
research perspectives. Washington, DC, US: American Psychiatric Association. pp. 363-381  Abstract: This chapter, while making reference to bipolar illness, is dedicated to discussion of the psychotherapeutic management of manic
patients. Psychotherapy in combination with lithium or other medications can be extremely beneficial in helping patients deal with issues and traumas in how they perceive themselves, are perceived by others, and interact with the outside world. Psychological support and therapy may also improve the individual's coping abilities and response to psychosocial stress in his or her life. Life stressors may play a role in precipitating affective episodes and may affect the outcome of illness. The optimum treatment regimen includes psychopharmacological
intervention and psychotherapy. Other topics discussed include: psychological issues; interpersonal behaviors and psychotherapeutic interventions.
  _____

Title: "Atypical bipolar symptoms": Reply.
Author(s): Wozniak, Janet , Harvard Medical School, Massachusetts General Hosp, Boston, MA, US; Biederman, Joseph
Source: Journal of the American Academy of Child & Adolescent Psychiatry , Vol 36(10), Oct 1997. pp. 1319-1320.
Publisher: US: Lippincott Williams & Wilkins.
Abstract: Replies to M. G. Burke's (1997) comments regarding the article by J. Wozniak and J. Biederman about
bipolar disorder in children. The authors answer Burke's questions regarding the etiology of bipolar disorder in the Wozniak and Biederman study. They note that a history of early trauma was not a contributing factor in Wozniak and Biederman's sample of manic children. The authors state that in their experience the majority of manic children come from
concerned and responsible families rather than abusive and neglectful ones. They suggest that clinicians who treat severely disturbed children with both trauma and bipolar disorder may erroneously attribute the direction of causation to be trauma leading to bipolar disorder, when in many cases the opposite may be true.
  _____

Title: Atypical bipolar symptoms.
Author(s): Burke, Mary G. , Mt St Joseph-St Elizabeth, San
Francisco, CA, US
Source: Journal of the American Academy of Child & Adolescent Psychiatry, Vol 36(10), Oct 1997. pp. 1319.
Publisher: US: Lippincott Williams & Wilkins.
Abstract: Comments on the articles by M. A. Fristad et al and J. Wozniak and J. Biederman regarding young people with bipolar disorder. The author suggests that the children described by Fristad et al and Wozniak and Biederman may have a history of early trauma, instead of the multiple genetic disorders suggested by the authors. A brief example of a young
female who had experienced near-catastrophic neglect and abuse by her cocaine abusing mother is presented to illustrate the similarities in symptoms between this S and Ss diagnosed with bipolar disorder. M. G. Burke asks Fristad et al as well as Wozniak and Biederman whether they are working with children with traumatic histories, or with children from caring, "good enough" families. Burke suggests that perhaps a new diagnostic entity to describe these children is needed.
  _____

Title: "Atypical bipolar symptoms": Reply.
Author(s): Fristad, Mary A. , Ohio State U, Columbus, OH, US; Weller, Ronald A.; Weller, Elizabeth B.
Source: Journal of the American Academy of Child & Adolescent Psychiatry , Vol 36(10), Oct 1997. pp. 1320.
Publisher: US: Lippincott Williams & Wilkins.
Abstract: Replies to the M. G. Burke's (1997) comments on M. A. Fristad et al's article regarding bipolar disorder in young people. To answer Burke's question regarding the etiology of bipolar disorder in Fristad et al's sample the authors
undertook a review of the histories of the bipolar children in the
sample. They found that their patients did not have a history of extreme early trauma. The authors, however, note that given the potential importance of the early history of bipolar children, they will conduct a more extensive review of their Ss which they will report at a later date.
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Translated Title: Psychological peculiarities of posttraumatic
stress states in veterans of the war in Afghanistan.
Author(s): Zelenova, Marina E., Russian Academy of Sciences, Inst of Psychology, Moscow, Russia; Lazebnaya, Elena O.; Tarabrina, Nadezhda V.
Source: Psikhologicheskiy Zhurnal , Vol 18(2), Mar-Apr 1997. pp. 34-49.
Publisher: Russia: Nauka Publishing House.
Abstract: Studied the psychological consequences of the
war-related posttraumatic stress experience of veterans of the war in Afghanistan. Human Ss: 65 normal male Russian adults (mean age 32.3 yrs) (veterans of the war in Afghanistan). 18 male Russian adults (mean age 31.1 yrs) (posttraumatic stress disorder, manifested or accompanied by depression, bipolar disorder, phobias, panic disorder, generalized anxiety, hypochondria, past or present alcoholism, and drug abuse)
(veterans of the war in Afghanistan). Ss were administered a psychodiagnostic interview, and the level of their war-related trauma was assessed. Demographic data, the frequency of manifestation of posttraumatic stress disorder (PTSD) symptoms and dissociative states, and drug use during the war were compared for the 2 groups. Tests used: The Structured Clinical Interview for Diagnostic and Statistical Manual
of Mental Disorders-III-Revised (DSM-III-R) Non-Patient Version and the Legacies Combat Exposure Scale (A. Egendorf et al, 1981).
  _____

Title: Life events and psychotic disorders.
Author(s): Bebbington, Paul , U London, Inst of Psychiatry, MRC Social & Community Psychiatry Unit, London, England; Bowen, Jo; Ramana, Rajini
Source: Miller, Thomas W. (Ed); 1997. Clinical disorders and
stressful life events. International Universities Press stress and
health series, Monograph 7. Madison, CT, US: International Universities Press, Inc. pp. 89-119
Abstract: This chapter addresses the impact of life events on
individuals and subsequent psychotic disorders. A review of the studies of life events and schizophrenia, together with 3 recent studies that address psychotic disorders and bipolar illness and event specificity contribute to our knowledge base in examining the psychotic components involved in victims' response to the traumatization process.
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Title: Obsessive-compulsive disorder. Familial-developmental history, symptomatology, comorbidity and course with special reference to gender-related differences.  Author(s): Lensi, Patrizia , U Pisa, Inst of Psychiatry, Pisa, Italy; Cassano, Giovanni B.; Correddu, Giuseppina; Ravagli, Susanna; Kunovac, Jelena J.
Source: British Journal of Psychiatry , Vol 169(1), Jul 1996.
pp. 101-107.
Publisher: England: Royal Coll of Psychiatrists.
Abstract: Investigated demographic data, family history,
psychopathological features, comorbidity, and course of
obsessive-compulsive disorder (OCD) to support the possible existence of 2 subgroups with gender-related differences. 263 Italian OCD patients were evaluated with a semistructured OCD interview. Results show a significantly greater history of perinatal trauma in OCD men, as well as earlier onset, greater likelihood of never having been married, and a higher frequency of sexual and symmetry obsessions and odd rituals; by
contrast, women suffered a later onset of the disorder, were more likely to be married, had higher rates of associated panic attacks after the onset of OCD and a higher frequency of aggressive obsessions at the onset of their illness, and were less frequently associated with bipolar disorders.
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Title: Psychostimulants apparently reverse sexual dysfunction secondary to selective serotonin re-uptake inhibitors.
Author(s): Bartlik, Barbara D. , New York Hosp-Cornell U Medical Coll, Dept of Psychiatry, US; Kaplan, Peter; Kaplan, Helen S.
Source: Journal of Sex & Marital Therapy , Vol 21(4), Win 1995. pp. 264-271.
Publisher: England: Taylor & Francis.
Abstract: Presents 4 cases of psychiatric patients (aged 23-49 yrs) in which low dosages of psychostimulants (dextroamphetamine and methylphenidate) reversed the sexually inhibiting side effects of the selective serotonin re-uptake inhibitors (SSRIs). Two patients suffered
from attention deficit hyperactivity disorder (ADHD), 1 from bipolar disorder (BD) and alcoholism, and 1 with BD and neurological trauma. After taking the psychostimulants, women experienced enhanced levels of arousal, orgasmic sensation, and excitement during the resolution phase of the sexual response cycle. Men were found to have improved erectile
strength. The fact that the majority of the patients on SSRIs seemed to experience an overall diminution in sexual functioning may have widespread implications. The disadvantages and precautions to be taken with the use of psychostimulants for enhancing sexual functioning are discussed.
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Title: Sexual victimization in women with schizophrenia and bipolar disorder.
Author(s): Darves-Bornoz, J.-M. , Ctr Hospitalier Universitaire de Tours, Clinique Psychiatrique Universitaire, France; Lemperiere, T.; Degiovanni, A.; Gaillard, P.
Source: Social Psychiatry & Psychiatric Epidemiology, Vol
30(2), Mar 1995. pp. 78-84.
Publisher: Germany: Springer-Verlag.
Abstract: Examined sexual victimization and its impact among 64 women with schizophrenia and 26 women with bipolar disorder who were interviewed with a clinician-rated battery of instruments and a semistructured questionnaire. In childhood or adolescence, 36% of schizophrenic Ss and 28% of bipolar disorder had been victims of sexual abuse involving body contact. In Ss with schizophrenia, this sexual abuse was associated with addictions, suicide attempts and becoming
psychiatric patients earlier. Over their lifetime, the prevalence of rape was 23% in both groups. In schizophrenic Ss, rape was associated with greater severity of disorder and addictions. Frequent repetition of sexual trauma was observed in schizophrenic Ss, whereas such traumas were less frequent in bipolar disorder Ss. Results suggest these Ss are at risk of rape.
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Title: Crisis and acute brief therapy with adolescents.
Author(s): Atlas, Jeffrey A. , Yeshiva U, Albert Einstein Coll of
Medicine, Bronx Children's Psychiatric Ctr, NY, US
Source: Psychiatric Quarterly , Vol 65(2), Sum 1994. Special
Issue: Brief and intermediate treatment for psychiatrically disturbed youth. pp. 79-87.
Publisher: US: Kluwer Academic/Plenum Publishers.
Abstract: Describes ways in which brief therapy approaches aimed at serving adults with neurotic or characterological problems in outpatient settings have been adapted for use with more disturbed adolescents in emergency room crisis work and acute inpatient hospital settings. The use of brief therapy approaches is illustrated in the treatment of a 15-yr-old girl suffering from bipolar disorder with elements of a brief reactive psychosis brought on by trauma.
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Title: The use of psychodynamic psychotherapy in manic-depressive illness.
Author(s): Kahn, David A. , Columbia U, Coll of Physicians &
Surgeons, New York, NY, US
Source: Journal of the American Academy of Psychoanalysis , Vol 21(3), Fal 1993. pp. 441-455.
Publisher: US: Guilford Publications.
Abstract: Examines a theoretical and practical basis for using
dynamic psychotherapy of personality in manic-depressive illness, mainly through trying to limit the stresses that precipitate affective episodes, in addition to autonomous, bipolar cycling. A psychodynamic viewpoint sees stress as a phenomenon closely related to the personality of the individual who must cope with stressful life events. In personality development, mild forms of affective illness resemble personality disorders, and the experience of having the illness produces certain kinds of trauma and confict. Case examples are presented of a 27-yr-old and a 37-yr-old woman, both rapid cyclers, one being a virgin until the age of 26 yrs and coming from a family with bipolar history and the other having been neglected, criticized, and sexually abused during childhood.
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Title: Trastorno bipolar postraumatico: a proposito de un caso.
Translated Title: Posttraumatic bipolar disorder: A case study.
Author(s): Pozo Navarro, P., Hosp General Universitario, Servicio de Psiquiatria Murcia, Spain; Navarro Mateu, F.; Salorio del Moral, P.; Santiuste de Pablos, M. et al.
Source: Anales de Psiquiatria , Vol 9(1), Jan 1993. pp. 48-51.
Publisher: Spain: Aran Ediciones SA.
Abstract: Discusses the use of carbamazepine with a 43-yr-old S with bipolar disorder due to brain trauma. The S exhibited depressive and manic symptoms. The S improved with carbamazepine treatment. Use of carbamazepine in other pathologies and etiopathogenic mechanisms are considered. (English abstract)
  _____

Title: Childhood origins of self-destructive behavior.
Author(s): Van der Kolk, Bessel A. , Erich Lindemann Mental Health Ctr, Trauma Clinic, Boston, MA, US; Perry, J. Christopher; Herman, Judith L.
Source: American Journal of Psychiatry , Vol 148(12), Dec 1991. pp. 1665-1671.
Publisher: US: American Psychiatric Assn.
Abstract: Explored the relations between childhood trauma,
disrupted attachment, and self-destruction in 74 Ss (aged 18-39 yrs) with personality disorders or bipolar II disorder. Ss were followed for an average of 4 yrs and monitored for self-destructive behavior such as suicide attempts, self-injury, and eating disorders. These behaviors were then correlated with self-reports of childhood trauma, disruptions of parental care, and dissociative phenomena. Histories of childhood sexual and physical abuse were significant predictors of self-cutting
and suicide attempts. During follow-up, Ss with the most severe histories of separation and neglect and those with past sexual abuse continued being self-destructive. The nature of the trauma and the S's age at the time of the trauma affected the character and the severity of the self-destructive behavior. Cutting was specifically related to dissociation.
  _____

Title: Frequency of occurrence of a WAIS dementia pattern in
schizophrenia and bipolar affective disorder.
Author(s): Ryan, Joseph J., Veterans Administration Medical Ctr, Psychology Service, Leavenworth, KS, US; Paolo, Anthony M.
Source: Clinical Neuropsychologist , Vol 3(1), Jan 1989. pp.
45-48.
Publisher: Netherlands: Swets & Zeitlinger.
Abstract: P. A. Fuld (1983) identified a Wechsler Adult
Intelligence Scale (WAIS) subtest profile that is moderately sensitive to the dementia associated with Alzheimer's disease but occurs infrequently in other conditions. 30 male chronic psychiatric patients (16 bipolar affective disorders; 14 schizophrenics) were examined for incidence of the pattern. Results indicate 97% specificity, since the pattern occurred in only 1 of the Ss. This compares favorably with reported figures for multi-infarct dementia (5.1%), craniocerebral trauma (5%), and normal elderly (<3%).
  _____

Title: Clinical perspectives on elderly first-offender shoplifters.
Author(s): Moak, Gary S., U Massachusetts Medical School,
Worcester, US; Zimmer, Ben; Stein, Elliott M.
Source: Hospital & Community Psychiatry , Vol 39(6), Jun 1988. pp. 648-651.
Publisher: US: American Psychiatric Assn.
Abstract: Suggests that the increase in shoplifting 1st offenses by people over the age of 60 yrs may be due not to economic hardship but to psychiatric disorders. The diagnostic criteria for kleptomania are summarized, and 4 cases of elderly patients whose shoplifting was a factor in their psychiatric diagnoses are presented. These diagnoses included bipolar disorder, dementia of the Alzheimer type, major depression, and kleptomania. Multidimensional psychiatric evaluation of
elderly 1st offenders is recommended and should take into account psychodynamic and neurobehavioral factors, as well as the psychiatric sequelae of the trauma of arrest and criminal processing.
  _____

Title: Camptocormia in a case of manic-depressive disorder.
Author(s): Gomez, Efrain A. , Baylor Coll of Medicine, Houston, TX, US; Drooby, A. S.
Source: Psychosomatics: Journal of Consultation Liaison
Psychiatry , Vol 28(11), Nov 1987. pp. 592, 594-595.
Publisher: US: American Psychiatric.
Abstract: Presents a case of camptocormia in a 36-yr-old male
veteran with manic depressive disorder. Camptocormia is a form of hysteria in which the S exhibits an awkward posture (trunk of the body at an angle of 30-7) following a trivial trauma. It is suggested that this presentation is important because it allows early diagnosis, effective treatment, and disposition. Recognition of secondary gain and its resolution is considered important in these cases.
  _____

Title: Mania following head trauma.
Author(s): Shukla, Sashi, State U New York, Health Sciences Ctr, Stony Brook; Cook, Brian L.; Mukherjee, Sukdeb; Godwin, Charles; et al.
Source: American Journal of Psychiatry , Vol 144(1), Jan 1987.
pp. 93-96.
Publisher: US: American Psychiatric Assn.
Abstract: Studied the phenomenological breakdown of symptoms and course of illness in 20 patients (aged 20-50 yrs) with posttraumatic mania and correlated the severity of the trauma with the Ss' psychiatric and neurologic symptoms. An association was found between severity of head trauma, posttraumatic seizure disorder, and type of bipolar disorder. Manic episodes were characterized by irritable mood and
assaultiveness. Psychosis occurred in only 15% of the sample, and 70% had no depressive episodes. Results suggest that posttraumatic seizures may be a predisposing factor in posttraumatic mania. (21 ref)
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Title: The role of deficiency and of affective trauma in the aetiology of the depressive state.
Author(s): Ionescu, George
Source: Revue Roumaine des Sciences Sociales - Serie de
Psychologie, Vol 31(1), Jan-Jun 1987. pp. 65-79.
Publisher: Romania: Editura Academiei Romane.
Abstract: Asserts that in the last 2 decades numerous studies have appeared that blame affective deficiencies in childhood for creating a psychological vulnerability for depression. Other, relatively recent studies highlight the psychostressful situations of milieu and in general the negative-affective life events, which are given the role of etiological factors. Analysis of specialty studies and clinical observations suggests that frustration and affective deficiencies cannot determine depression in adulthood; they only produce a certain
vulnerability to depression. The life events that precede at certain intervals the onset of the depression have only the role of releasing a psychopathological potential created by psychological vulnerability that is correlated with genetic and chemical factors.
  _____

Translated Title: The structure of mental diseases of the second half of life: An epidemiological study.
Author(s): Khokhlov, L. K. , Yaroslavl State Medical Inst, Dept of Psychiatry, USSR; Saveliev, L. N.; Ilyina, V. N.; Gavrilov, V. V.
Source: Zhurnal Nevropatologii i Psikhiatrii imeni S.S.
Korsakova, Vol 86(9), 1986. pp. 1349-1352.
Publisher: Russia: Izdatel'stvo 'Medicina'.
Abstract: Studied all patients, except alcoholics, residing in a
city district and registered at a psychoneurological clinic in the USSR. Human subjects: Russian adults (vascular pathology, involutional psychoses, presenile dementia, senile dementia, schizophrenia, manic-depressive psychosis, sequelae of head trauma). The age at disease onset, clinical symptoms, disease course, prognosis, and level of social adaptation were studied. (English abstract)
  _____

Title: Manic-depressive disorder in children and adolescents.
Author(s): Feinstein, Sherman C., U Chicago, Pritzker School of Medicine
Source: Adolescent Psychiatry , Vol 10, 1982. pp. 256-272.
Publisher: US: University of Chicago Press.
Abstract: Addresses clinical aspects of manic-depressive (MD)
illness in children, asserting that the disorder may show specific
equivalent behaviors that are the precursors of the cyclothymic
personality and MD states of young adulthood. Three case examples of juvenile manic-depression are presented, in which Ss' periodic and alternating affective disorders are described. It is argued that the affective systems of children with MD illness may display a basic vulnerability that, when overstimulated, begins a discharge pattern that does not lend itself easily to autonomous emotional control. MD disorder may appear in early childhood, manifesting itself as erratic, rapidly shifting mood behavior with a basically intact intellect. The apparent
lack of precipitating trauma may be explained by the pronounced sensitivity of these children to loss or the fear of loss, which triggers a distinct affective episode. The effectiveness of lithium carbonate makes the early diagnosis of MD disorder necessary. Lithium carbonate is useful in the treatment of juvenile MD illness, and its use is described. It is concluded that there is a need for psychotherapy to
facilitate acceptance of the disorder and to avoid characterological defect. (42 ref)
  _____

Title: Anniversary reactions masquerading as manic-depressive illness.
Author(s): Cavenar, Jesse O. , VA Hosp Psychiatry Service, Durham, NC; Nash, James L.; Maltbie, Allan A.
Source: American Journal of Psychiatry , Vol 134(11), Nov 1977. pp. 1273-1276.
Publisher: US: American Psychiatric Assn.
Abstract: Suggests that many patients diagnosed as having
manic-depressive illness, depressed type, may in fact be experiencing anniversary reactions--time-specific psychological and physiological reactions to a past trauma. Three cases are presented of cyclic depressive disorder, 2 of which were first diagnosed as manic-depressive illness, depressed type. Careful, complete interviewing and attention to temporal sequence led to the correct diagnosis of anniversary reaction. (16 ref)
  _____

Title: Juvenile manic-depressive illness: Clinical and therapeutic
considerations.
Author(s): Feinstein, Sherman C. , Michael Reese Hosp., Inst. for Psychosomatic & Psychiatric Research & Training, Chicago, Ill; Wolpert, Edward A.
Source: Journal of the American Academy of Child Psychiatry,
Vol. 12(1), Jan 1973. pp. 123-136.
Publisher: US: Lippincott Williams & Wilkins.
Abstract: Presents an example of a child with periodic alternating affective disorder as a case of juvenile manic-depressive illness. It is postulated that manic-depressive illness appears in early childhood, manifesting itself as erratic, rapidly shifting mood behavior with a basic intactness of intellect. The literature describing genetic and biochemical research is discussed. The effectiveness of lithium carbonate makes the early diagnosis of manic-depressive illness necessary. Psychotherapy is of great importance in the treatment plan in
order to help the child deal with problems of separation-individuation and loss and to help resolve severe fixations which could develop while the child is struggling with the overwhelming psychic trauma of the illness and its threat to the ego defenses. (21 ref.)
  _____

Translated Title: Childhood manic-depressive illness: Clinical and therapeutic considerations.
Author(s): Feinstein, Sherman C., Michael Reese Hosp. & Medical Center, Chicago, Ill; Wolpert, Edouard A.
Source: Psychiatrie de l'Enfant , Vol. 15(1), 1972. pp. 133-147.
Publisher: France: Presses Universitaires de France.
Abstract: Discusses the literature and clinical data which support the thesis that manic-depressives show, as children, specific behavior which is the precursor of a thymocyclic personality and the manic-depressive state of an adult. In certain cases, a juvenile version of this disorder also is manifested. It is postulated that the characteristics of the manic-depressive child appear in the form of  bizarre behavior, unstable temperament, and a fundamentally intact intellect. The lack of a precipitating trauma is explained by an acute
sensibility to loss or the fear of loss (of a parent) which leads to emotional episodes. The case history of a 31/2-yr-old girl is presented to show the S's affective development and her response to different types of treatment. An analysis of genetic and biochemical research reveals that lithium carbonate is helpful in permitting an early diagnosis of manic depression and in its treatment. Psychotherapy is considered important in helping the child (a) face separation-individuation and loss problems, and (b) resolve fixations which are established in his struggle against psychic traumas and ego threats. The consequences of loss experiences are described as are the
effects of growth and development in the course of therapy and the results of long-term therapy. (21 ref.)

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